"Venezuela today is the object of aggression from a number of satellite countries of the United States - those countries that organized this amazing farce century called humanitarian aid for Venezuela," she said at a meeting with State Duma Chairman Vyacheslav Volodin.
She stressed that the purpose of this action is not to provide real assistance to the population, but to organize unrest in the country.
According to Rodriguez, the reaction of President Nicolas Maduro to such actions was the further strengthening of relations with Russia.
Earlier, the head of the National Assembly of Venezuela, Juan Guaido, announced the delivery of another batch of humanitarian aid from the United States to the Colombian city of Cucuta.
Bolivian leader Evo Morales called humanitarian aid to Venezuela a "Trojan horse" for intervention and military provocation.